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BT Lab

SKU:BT-AP15604

FKBP4 Polyclonal Antibody

FKBP4 Polyclonal Antibody

Regular price $275.00 USD
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein corr

The FKBP4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of FKBP4 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity towards FKBP4.

FKBP4, also known as FK506-binding protein 4 or FKBP52, is a member of the immunophilin protein family and plays a crucial role in various cellular processes, including protein folding, trafficking, and signal transduction. It is predominantly localized in the cytoplasm and has been implicated in the regulation of steroid hormone receptor activity, particularly the androgen receptor and glucocorticoid receptor.

The FKBP4 Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

With its high affinity and specificity, this antibody offers researchers a valuable tool for studying the function and regulation of FKBP4 in diverse biological systems. Its exceptional performance and reliability make it an indispensable asset for any laboratory conducting research in the field of cellular biology, molecular biology, and immunology.

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