Fhit(Phospho Tyr114) Polyclonal Antibody

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

The Fhit(Phospho Tyr114) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Fhit protein phosphorylated at Tyr114 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The Fhit protein plays a crucial role in various cellular processes, including DNA damage repair, cell cycle regulation, and tumor suppression. Phosphorylation of the Tyr114 residue has been implicated in the modulation of Fhit protein function and its involvement in signaling pathways.

This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of Fhit protein phosphorylated at Tyr114 residue in complex biological samples.

The Fhit(Phospho Tyr114) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and versatility, the Fhit(Phospho Tyr114) Polyclonal Antibody is an indispensable tool for researchers studying Fhit protein phosphorylation and its functional implications in various biological processes.