FAS(Phospho Tyr291) Polyclonal Antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, s

The FAS (Phospho Tyr291) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FAS protein phosphorylated at tyrosine 291. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

FAS, also known as CD95 or APO-1, is a transmembrane protein belonging to the tumor necrosis factor receptor superfamily. It plays a crucial role in the regulation of apoptosis, or programmed cell death, and is involved in various physiological and pathological processes, including immune response, development, and cancer.

Phosphorylation of FAS at tyrosine 291 has been shown to modulate its signaling pathway and influence its biological functions. The FAS (Phospho Tyr291) Polyclonal Antibody specifically recognizes and binds to the phosphorylated form of FAS at this site, enabling researchers to study the activation and regulation of FAS-mediated signaling pathways.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, allowing for accurate and reliable detection of phosphorylated FAS in complex biological samples.

The FAS (Phospho Tyr291) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effective and efficient experiments. Each batch of antibody undergoes rigorous quality control procedures to ensure consistent and reliable performance.

In summary, the FAS (Phospho Tyr291) Polyclonal Antibody is a valuable tool for researchers studying FAS signaling and its role in various biological processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, enabling in-depth investigations into the phosphorylation-dependent regulation of FAS-mediated pathways.

The FAS(Phospho Tyr291) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of FAS protein phosphorylated at tyrosine 291. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The FAS protein, also known as CD95 or APO-1, plays a crucial role in the regulation of apoptosis, or programmed cell death. Phosphorylation of FAS at tyrosine 291 has been implicated in various cellular processes, including cell survival, proliferation, and differentiation. Therefore, the ability to accurately detect and quantify this phosphorylation event is of utmost importance in understanding the intricate mechanisms underlying these processes.

The FAS(Phospho Tyr291) Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been rigorously validated for its specificity and sensitivity, ensuring reliable and reproducible results. This antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its superior quality and performance, the FAS(Phospho Tyr291) Polyclonal Antibody is an indispensable tool for researchers and scientists working in the fields of cell biology, cancer research, and immunology. Its ability to accurately detect and quantify FAS phosphorylation at tyrosine 291 opens up new avenues for understanding the complex signaling pathways involved in cellular processes and disease progression.