FAK(Phospho Tyr407) Polyclonal Antibody

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.

The FAK (Phospho Tyr407) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Focal Adhesion Kinase (FAK) phosphorylated at tyrosine 407. FAK is a crucial protein involved in cell adhesion, migration, and signaling pathways, making it an essential target for research in various fields, including cancer biology, developmental biology, and immunology.

This polyclonal antibody has been meticulously developed and rigorously validated to ensure its reliability and accuracy in detecting FAK phosphorylated at tyrosine 407. It exhibits exceptional specificity, exhibiting minimal cross-reactivity with non-phosphorylated FAK or other related proteins. This specificity allows for precise and reliable quantification of FAK phosphorylation levels in various biological samples.

The FAK (Phospho Tyr407) Polyclonal Antibody demonstrates exceptional sensitivity, enabling the detection of low levels of FAK phosphorylation. This sensitivity is crucial for researchers aiming to study subtle changes in FAK phosphorylation under different experimental conditions or disease states.

Furthermore, this antibody has been extensively tested in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence. Its versatility allows for seamless integration into various experimental protocols, providing researchers with flexibility and convenience.

In summary, the FAK (Phospho Tyr407) Polyclonal Antibody is a highly reliable and sensitive tool for the detection and quantification of FAK phosphorylated at tyrosine 407. Its exceptional specificity and sensitivity, along with its versatility in various applications, make it an invaluable asset for researchers investigating FAK signaling pathways and its implications in various biological processes.