Ezrin(Phospho Tyr478) Polyclonal Antibody

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

The Ezrin(Phospho Tyr478) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Ezrin protein phosphorylated at Tyr478. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

Ezrin is a member of the ERM (ezrin, radixin, moesin) protein family, which plays a crucial role in the organization and maintenance of the cytoskeleton. Phosphorylation of Ezrin at Tyr478 has been implicated in various cellular processes, including cell adhesion, migration, and signaling. Therefore, the ability to accurately measure the phosphorylation status of Ezrin at Tyr478 is of great importance in understanding its functional role in different biological contexts.

The Ezrin(Phospho Tyr478) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of Ezrin at Tyr478, enabling precise detection and quantification of this modified protein. It has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence, ensuring its suitability for a wide range of applications.

This antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The high affinity and sensitivity of this antibody ensure reliable and reproducible results, even with low abundance samples.

In summary, the Ezrin(Phospho Tyr478) Polyclonal Antibody is a valuable tool for researchers studying the phosphorylation status of Ezrin at Tyr478. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications in cell biology, molecular biology, and related fields.