Ezrin(Phospho Tyr146) Polyclonal Antibody

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

The Ezrin(Phospho Tyr146) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Ezrin protein phosphorylated at Tyr146. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

Ezrin is a member of the ERM (ezrin, radixin, moesin) protein family, which plays a crucial role in the organization and maintenance of the cytoskeleton. Phosphorylation of Ezrin at Tyr146 has been implicated in various cellular processes, including cell adhesion, migration, and signaling. Therefore, the ability to accurately measure the levels of phosphorylated Ezrin is of great importance in understanding its functional significance.

The Ezrin(Phospho Tyr146) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of Ezrin, enabling precise detection and quantification in various biological samples. It has been extensively validated in multiple experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The product is accompanied by comprehensive technical documentation, including recommended protocols and storage conditions, to facilitate successful experimentation.

In summary, the Ezrin(Phospho Tyr146) Polyclonal Antibody is a reliable and efficient tool for researchers studying the phosphorylation status of Ezrin. Its high specificity, sensitivity, and versatility make it an invaluable asset in elucidating the complex mechanisms underlying cellular processes.