Ets-1(Phospho Ser251) Polyclonal Antibody

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

The Ets-1(Phospho Ser251) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Ets-1 protein phosphorylated at Ser251. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity for the target protein.

Ets-1 is a transcription factor that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and migration. Phosphorylation of Ets-1 at Ser251 has been implicated in the regulation of its transcriptional activity and downstream signaling pathways. Therefore, the ability to accurately measure the phosphorylation status of Ets-1 at Ser251 is of great importance in understanding its functional role in cellular processes.

The Ets-1(Phospho Ser251) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Ets-1 and other related proteins, ensuring reliable and accurate results.

This antibody is supplied as a liquid formulation, ready for immediate use in various applications, including but not limited to Western blotting, immunohistochemistry, and flow cytometry. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and reliability, the Ets-1(Phospho Ser251) Polyclonal Antibody is an indispensable tool for researchers studying the role of Ets-1 phosphorylation in cellular processes. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.