ER beta(Phospho Ser87) Polyclonal Antibody

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

The ER beta(Phospho Ser87) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated Serine 87 of the ER beta protein. This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ER beta protein plays a crucial role in the regulation of estrogen signaling and is involved in numerous physiological processes, such as cell proliferation, differentiation, and apoptosis. Phosphorylation of Serine 87 has been shown to modulate the activity and function of ER beta, making it an important target for research in the field of hormone signaling and related diseases.

Our ER beta(Phospho Ser87) Polyclonal Antibody has been developed using state-of-the-art techniques and high-quality materials to ensure optimal performance and reproducibility. It exhibits exceptional specificity, with minimal cross-reactivity to other phosphorylated or non-phosphorylated residues of ER beta or other related proteins.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been extensively tested and validated in various cell lines and tissues, ensuring reliable and consistent results. The antibody is provided in a convenient size, allowing for multiple experiments and minimizing waste.

With its superior sensitivity and specificity, the ER beta(Phospho Ser87) Polyclonal Antibody is an invaluable tool for researchers studying estrogen signaling pathways and related diseases. Its versatility and reliability make it suitable for a wide range of applications, enabling detailed investigations into the role of ER beta phosphorylation in cellular processes and disease progression.

Order your ER beta(Phospho Ser87) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of estrogen signaling.