ER alpha(Phospho Ser167) Polyclonal Antibody

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

The ER alpha(Phospho Ser167) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Ser167 of the estrogen receptor alpha (ER alpha) protein. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The ER alpha(Phospho Ser167) Polyclonal Antibody exhibits exceptional affinity and selectivity towards the phosphorylated Ser167 residue of ER alpha. It has been extensively validated and characterized to guarantee accurate and reproducible results in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody offers researchers a valuable tool to investigate the phosphorylation status of ER alpha at Ser167, a critical post-translational modification that plays a crucial role in the regulation of ER alpha activity and downstream signaling pathways. By targeting this specific phosphorylation site, researchers can gain insights into the molecular mechanisms underlying estrogen signaling and its implications in various physiological and pathological processes.

The ER alpha(Phospho Ser167) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional specificity, sensitivity, and versatility, the ER alpha(Phospho Ser167) Polyclonal Antibody is an indispensable tool for researchers studying estrogen receptor signaling and its involvement in various biological processes. Its reliable performance and reproducibility make it an ideal choice for both basic research and clinical applications.