ER alpha(Phospho Ser102) Polyclonal Antibody

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

The ER alpha(Phospho Ser102) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated Ser102 of the estrogen receptor alpha (ER alpha) protein. This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ER alpha(Phospho Ser102) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated Ser102 residue of ER alpha, enabling researchers to accurately assess the activation status of this important protein. This antibody recognizes the phosphorylated form of ER alpha with high affinity, while exhibiting minimal cross-reactivity with non-phosphorylated ER alpha or other related proteins.

With its superior sensitivity, the ER alpha(Phospho Ser102) Polyclonal Antibody allows for the detection of even low levels of phosphorylated ER alpha, making it an ideal tool for studying the regulation and signaling pathways involving this protein. Its robust performance in various experimental techniques ensures reliable and reproducible results, facilitating the advancement of research in the field of estrogen receptor biology.

The ER alpha(Phospho Ser102) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its high-quality formulation ensures consistent and reliable performance, enabling researchers to focus on their experiments without concerns about antibody quality.

In summary, the ER alpha(Phospho Ser102) Polyclonal Antibody is a valuable tool for investigating the phosphorylation status of ER alpha protein. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset for researchers studying estrogen receptor biology and related fields.