ERK 5 Polyclonal Antibody

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

The ERK 8(Phospho Thr175/Y177) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated ERK 8 protein. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The ERK 8(Phospho Thr175/Y177) Polyclonal Antibody is raised in rabbits and purified using a combination of affinity chromatography and protein A/G purification methods. This rigorous purification process guarantees a high level of purity and specificity, minimizing the risk of cross-reactivity with non-target proteins.

This antibody has been validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated ERK 8 protein in various biological samples.

The ERK 8(Phospho Thr175/Y177) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 1 mg/mL concentration, ensuring sufficient antibody for multiple experiments. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional performance and reliability, the ERK 8(Phospho Thr175/Y177) Polyclonal Antibody is an indispensable tool for researchers studying ERK 8 signaling pathways and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for accurate and precise detection of phosphorylated ERK 8 protein, facilitating further understanding of its function and potential therapeutic applications.