ERD21 Polyclonal Antibody

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to t

The ERD21 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ERD21 protein expression in various biological samples. This antibody is produced through a rigorous process of immunization using a synthetic peptide corresponding to a specific region of the ERD21 protein.

The ERD21 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to provide accurate and reproducible results.

With its superior performance, the ERD21 Polyclonal Antibody enables researchers to gain valuable insights into the function and regulation of the ERD21 protein in different cellular processes. Its versatility and reliability make it an indispensable tool for studying protein-protein interactions, cellular localization, and protein expression dynamics.

The ERD21 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. It is available in various sizes to accommodate different experimental needs.

Choose the ERD21 Polyclonal Antibody for its exceptional quality, reliability, and versatility, and unlock the potential of your research in the field of ERD21 protein analysis.