EphB3 Polyclonal Antibody

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

The Ephrin-B1(Phospho Tyr317) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Ephrin-B1 protein phosphorylated at Tyr317 residue. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The Ephrin-B1 protein plays a crucial role in various cellular processes, including cell adhesion, migration, and axon guidance. Phosphorylation of the Tyr317 residue has been implicated in the regulation of Ephrin-B1 signaling pathways, making it an important target for research in the field of cell biology and signal transduction.

This polyclonal antibody is generated by immunizing animals with a synthetic phospho-peptide corresponding to the region surrounding Tyr317 of Ephrin-B1. It has been extensively validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence.

The Ephrin-B1(Phospho Tyr317) Polyclonal Antibody exhibits excellent performance in detecting endogenous levels of phosphorylated Ephrin-B1 protein in various cell and tissue lysates. It demonstrates minimal cross-reactivity with non-phosphorylated Ephrin-B1 and other related proteins, ensuring accurate and reliable results.

With its high specificity and sensitivity, this antibody is an invaluable tool for researchers studying Ephrin-B1 signaling pathways and its role in various physiological and pathological processes. It provides a reliable means to investigate the phosphorylation status of Ephrin-B1 and its functional implications in cellular processes.

In summary, the Ephrin-B1(Phospho Tyr317) Polyclonal Antibody is a high-quality research reagent that offers exceptional performance in the detection and analysis of phosphorylated Ephrin-B1 protein. Its specificity, sensitivity, and reliability make it an essential tool for researchers in the field of cell biology and signal transduction.