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SKU:BT-AP15432

EphA2/5(Phospho Tyr594) Polyclonal Antibody

EphA2/5(Phospho Tyr594) Polyclonal Antibody

Regular price $275.00 USD
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This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

The EphA2/5(Phospho Tyr594) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of EphA2/5 protein phosphorylated at Tyr594 residue. This antibody is produced using advanced immunization techniques, resulting in a high affinity and specificity towards the phosphorylated form of EphA2/5.

The EphA2/5 receptor tyrosine kinases play crucial roles in various cellular processes, including cell adhesion, migration, and proliferation. The phosphorylation of EphA2/5 at Tyr594 residue has been implicated in the regulation of these processes, making it an important target for research in the field of cell biology and cancer biology.

This polyclonal antibody is rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated EphA2/5 and other related proteins, ensuring accurate and reliable results.

The EphA2/5(Phospho Tyr594) Polyclonal Antibody is supplied as a liquid formulation, ready to use for various applications in molecular biology and biomedical research. It is suitable for use in both in vitro and in vivo studies, enabling researchers to investigate the role of EphA2/5 phosphorylation in cellular signaling pathways and disease progression.

With its exceptional performance and high specificity, the EphA2/5(Phospho Tyr594) Polyclonal Antibody is an indispensable tool for scientists and researchers working in the fields of cell biology, cancer biology, and drug discovery. Its reliable and reproducible results make it an ideal choice for studying the functional significance of EphA2/5 phosphorylation and its potential as a therapeutic target.

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