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SKU:BT-AP15400

Endoglin Polyclonal Antibody

Endoglin Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The Endoglin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of endoglin protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

The Endoglin Polyclonal Antibody exhibits exceptional affinity and specificity towards endoglin, a transmembrane glycoprotein that plays a crucial role in angiogenesis and vascular development. It is widely expressed in endothelial cells and is involved in various physiological and pathological processes, including tumor angiogenesis, inflammation, and cardiovascular diseases.

This antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and flow cytometry. It has been rigorously tested and proven to provide reliable and reproducible results across a wide range of sample types, including cell lysates, tissue sections, and whole blood.

The Endoglin Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing waste. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

With its exceptional sensitivity and specificity, the Endoglin Polyclonal Antibody is an indispensable tool for researchers and clinicians studying endoglin-related diseases and exploring potential therapeutic interventions. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.

Order the Endoglin Polyclonal Antibody today and unlock new insights into the role of endoglin in various biological processes, paving the way for advancements in disease diagnosis, prognosis, and treatment.

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