ELNE Polyclonal Antibody

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.

The ELNE Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of elastase, a key enzyme involved in various physiological and pathological processes. This antibody is produced using state-of-the-art technology, ensuring exceptional quality and performance.

The ELNE Polyclonal Antibody exhibits a high affinity for elastase, enabling accurate and reliable results in a wide range of applications, including immunohistochemistry, western blotting, and enzyme-linked immunosorbent assays (ELISA). Its exceptional specificity ensures minimal cross-reactivity with other related proteins, guaranteeing precise and reproducible data.

This antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The ELNE Polyclonal Antibody is compatible with various sample types, including tissue lysates, cell lysates, and biological fluids, facilitating versatile experimental designs.

The ELNE Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability. It is validated for use in both research and diagnostic applications, making it an ideal choice for academic institutions, pharmaceutical companies, and clinical laboratories.

In summary, the ELNE Polyclonal Antibody is a highly specific and sensitive tool that offers exceptional performance in the detection and quantification of elastase. With its outstanding specificity, ease of use, and compatibility with various applications and sample types, this antibody is an invaluable asset for researchers and clinicians alike.