EGFR(Phospho-Tyr998) Polyclonal Antibody

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

The EGFR(Phospho-Tyr998) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated tyrosine 998 on the epidermal growth factor receptor (EGFR) protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity.

The EGFR protein plays a crucial role in cell growth, proliferation, and differentiation, making it an important target for research in various fields, including cancer biology and signal transduction. Phosphorylation of tyrosine 998 on EGFR has been implicated in the activation of downstream signaling pathways, leading to cellular responses such as cell survival, migration, and angiogenesis.

The EGFR(Phospho-Tyr998) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated EGFR and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, suitable for both small-scale and large-scale experiments. The EGFR(Phospho-Tyr998) Polyclonal Antibody is compatible with a wide range of applications, including but not limited to, immunohistochemistry, flow cytometry, and enzyme-linked immunosorbent assay (ELISA).

With its exceptional specificity, sensitivity, and versatility, the EGFR(Phospho-Tyr998) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the role of EGFR phosphorylation in various biological processes. Its reliable performance and reproducibility make it an ideal choice for both basic research and drug development studies.