EGFR(Phospho Tyr1197) Polyclonal Antibody

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

The EGFR(Phospho Tyr1197) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated tyrosine 1197 on the epidermal growth factor receptor (EGFR) protein. This antibody is produced using a polyclonal approach, ensuring a diverse population of antibodies that can recognize and bind to the phosphorylated form of EGFR with high affinity and specificity.

The EGFR protein plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. Phosphorylation of tyrosine 1197 on EGFR is known to be a key event in the activation of downstream signaling pathways, leading to cellular responses such as cell growth and migration. Therefore, the ability to specifically detect and quantify phosphorylated tyrosine 1197 on EGFR is of great importance in understanding the molecular mechanisms underlying EGFR signaling and its implications in various diseases, including cancer.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated forms of EGFR and other related proteins, ensuring accurate and reliable results.

The EGFR(Phospho Tyr1197) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use in various applications, including but not limited to Western blotting, immunoprecipitation, immunofluorescence, and flow cytometry. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its high specificity, sensitivity, and versatility, the EGFR(Phospho Tyr1197) Polyclonal Antibody is an indispensable tool for researchers and scientists studying EGFR signaling pathways and its involvement in various diseases. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.