DUSP6 Polyclonal Antibody

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in t

The DUSP6 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Dual Specificity Phosphatase 6 (DUSP6) protein. This antibody is produced using advanced techniques to ensure superior quality and performance.

DUSP6 is a member of the dual specificity phosphatase family, which plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and survival. It acts as a negative regulator of mitogen-activated protein kinase (MAPK) signaling pathways by dephosphorylating and inactivating extracellular signal-regulated kinases 1 and 2 (ERK1/2).

The DUSP6 Polyclonal Antibody exhibits exceptional specificity towards DUSP6 protein, enabling precise detection and quantification in various biological samples. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence applications.

This antibody is manufactured using high-quality materials and undergoes rigorous quality control procedures to ensure batch-to-batch consistency and reproducibility. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The DUSP6 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is stable under recommended storage conditions, ensuring long-term usability.

In summary, the DUSP6 Polyclonal Antibody is a valuable tool for researchers studying the role of DUSP6 in cellular signaling pathways. Its high specificity, reliability, and ease of use make it an ideal choice for various experimental applications.