DSC3 Polyclonal Antibody

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

The DSC3 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The DSC3 Polyclonal Antibody is ideal for use in immunohistochemistry, western blotting, and other applications where high sensitivity and specificity are required.

This antibody is designed to target the DSC3 protein, which is a member of the desmocollin family of proteins. The DSC3 protein is involved in the formation of desmosomes, which are important for maintaining the structural integrity of tissues. The DSC3 Polyclonal Antibody is highly specific for the DSC3 protein and does not cross-react with other members of the desmocollin family.

The DSC3 Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure its quality and consistency. This antibody is supplied in a convenient format and is ready to use in a variety of applications.

In summary, the DSC3 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for use in various research applications. Its specificity for the DSC3 protein and its high sensitivity make it an excellent tool for studying the role of desmosomes in tissue structure and function.