DRP1(Phospho Ser637) Polyclonal Antibody

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

The DRP1(Phospho Ser637) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of DRP1 protein phosphorylated at Serine 637. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards the target epitope.

DRP1, also known as dynamin-related protein 1, plays a crucial role in mitochondrial fission, a process essential for maintaining mitochondrial dynamics and cellular homeostasis. Phosphorylation of DRP1 at Serine 637 has been implicated in regulating its activity and subcellular localization, making it a key phosphorylation site of interest in various cellular processes.

The DRP1(Phospho Ser637) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated DRP1 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for compatibility with a wide range of experimental conditions, ensuring consistent and reproducible results across different research settings. Additionally, it is provided in a convenient size, allowing for cost-effective and efficient usage.

Researchers and scientists working in the fields of cell biology, mitochondrial dynamics, and signal transduction will greatly benefit from the DRP1(Phospho Ser637) Polyclonal Antibody. Its exceptional performance and reliability make it an indispensable tool for investigating the role of DRP1 phosphorylation in various physiological and pathological processes.

In summary, the DRP1(Phospho Ser637) Polyclonal Antibody offers a highly specific and sensitive solution for the detection and quantification of phosphorylated DRP1 protein. With its advanced production techniques, rigorous validation, and compatibility with various applications, this antibody is an invaluable asset for researchers aiming to unravel the intricate mechanisms underlying mitochondrial dynamics and cellular homeostasis.