DRA Polyclonal Antibody

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

The DRA Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of the DRA protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The DRA Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other proteins to ensure minimal interference and reliable performance.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is compatible with various sample types, including cell lysates, tissue homogenates, and serum.

The DRA Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is provided in a liquid formulation, ensuring ease of use and minimizing the risk of sample contamination.

With its exceptional performance and reliability, the DRA Polyclonal Antibody is an indispensable tool for researchers and scientists working in the field of molecular biology and protein analysis. It enables accurate and precise detection of the DRA protein, facilitating further understanding of its role in various biological processes.