DQB2 Polyclonal Antibody

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQ

The DQB2 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in a variety of research applications. This antibody has been raised against the DQB2 protein, which is a member of the major histocompatibility complex (MHC) class II molecules. The DQB2 Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and flow cytometry applications.

This antibody has been purified using a combination of protein A and protein G chromatography, ensuring high purity and specificity. The DQB2 Polyclonal Antibody has been shown to recognize both the native and denatured forms of the DQB2 protein, making it an ideal tool for studying the expression and function of this important protein.

The DQB2 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. This antibody is available in a range of sizes to suit your specific needs, and is suitable for use in a variety of research applications.

Overall, the DQB2 Polyclonal Antibody is a highly reliable and specific tool for studying the DQB2 protein in a variety of research applications. Its high sensitivity and specificity make it an ideal choice for researchers looking to study the expression and function of this important protein.