DOC11 Polyclonal Antibody

The DHR-2 domain is necessary for the GEF activity.,Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR-1 (CZH-1) domain.,Contains 1 DHR-2 (CZH-2) domain.,Contains 1 PH domain.,subunit:Interacts with CDC42.,

The DOC11 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of DOC11 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human DOC11 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards DOC11 protein, making it an ideal tool for various applications in research and diagnostics.

The DOC11 Polyclonal Antibody is validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It recognizes a single band of approximately 40 kDa in Western blot analysis of human cell lysates, and shows strong staining of DOC11 protein in formalin-fixed, paraffin-embedded human tissues. In addition, this antibody has been shown to be highly sensitive and specific in detecting DOC11 protein in various cell lines and tissues.

The DOC11 Polyclonal Antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications. It is recommended to use this antibody at a dilution of 1:1000 for Western blotting, and at a dilution of 1:50-1:100 for immunohistochemistry and immunofluorescence assays. This antibody is suitable for use in both research and diagnostic applications, and is an essential tool for studying the function and regulation of DOC11 protein in various biological processes.