DNER Polyclonal Antibody

Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,Contains 1 follistatin-like domain.,Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,

The DNER Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of Delta/Notch-like EGF-related receptor (DNER) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human DNER protein, followed by affinity purification using a DNER-specific antigen. The resulting polyclonal antibody exhibits excellent specificity and affinity towards DNER protein, with minimal cross-reactivity to other related proteins.

The DNER Polyclonal Antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence assays. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous DNER protein expression in various tissues, including brain, spinal cord, and lymphoid organs.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C or below for long-term storage, and to avoid repeated freeze-thaw cycles.

In summary, the DNER Polyclonal Antibody is a reliable and high-quality tool for the detection and quantification of DNER protein in various biological samples. Its excellent specificity and sensitivity make it an ideal choice for researchers studying the role of DNER in various physiological and pathological processes.