DMBT1 Polyclonal Antibody

Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

The DMBT1 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of DMBT1 protein expression. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The DMBT1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the DMBT1 protein, enabling accurate and reliable detection even at low expression levels. Its polyclonal nature allows for enhanced sensitivity and versatility, making it an ideal choice for researchers and scientists working in diverse fields such as cancer research, immunology, and molecular biology.

This antibody has been produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. Its exceptional specificity minimizes the risk of cross-reactivity with other proteins, guaranteeing reliable and reproducible results. Furthermore, the DMBT1 Polyclonal Antibody has been extensively validated using a variety of experimental approaches, ensuring its reliability and accuracy.

With its superior performance characteristics, the DMBT1 Polyclonal Antibody offers researchers a valuable tool for investigating the role of DMBT1 protein in various biological processes and disease states. Its versatility and sensitivity make it an indispensable asset for elucidating the molecular mechanisms underlying DMBT1-related pathologies and for identifying potential therapeutic targets.

In summary, the DMBT1 Polyclonal Antibody is a meticulously developed and rigorously validated immunological tool that offers exceptional sensitivity, specificity, and versatility. Its high performance characteristics make it an invaluable asset for researchers seeking to unravel the complexities of DMBT1 protein function and its implications in various biological processes and diseases.