DMA Polyclonal Antibody

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

The DMA Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of DNA methyltransferase A (DMA) protein in various biological samples. This antibody is produced using a unique and advanced polyclonal antibody production process, ensuring high affinity and specificity towards DMA protein.

The DMA Polyclonal Antibody exhibits exceptional sensitivity, enabling accurate and precise measurement of DMA protein levels even at low concentrations. It has been extensively validated through rigorous testing, guaranteeing consistent and reproducible results across different experimental conditions.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for the investigation of DMA protein expression and localization in diverse cell types and tissues.

The DMA Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming antibody preparation.

With its exceptional performance and reliability, the DMA Polyclonal Antibody is an indispensable tool for researchers and scientists studying DNA methyltransferase A and its role in epigenetic regulation.