BT Lab
SKU:BT-AP08370
DAG1 Polyclonal Antibody
DAG1 Polyclonal Antibody
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This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
The DAG1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of dystroglycan 1 (DAG1) protein. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.
DAG1, a transmembrane glycoprotein, plays a crucial role in maintaining the integrity and stability of muscle tissues. It is a key component of the dystrophin-glycoprotein complex, which is essential for proper muscle function. Dysregulation or mutations in DAG1 have been associated with various muscular dystrophies and other neuromuscular disorders.
The DAG1 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of DAG1 protein levels in various biological samples. It has been extensively validated for use in immunohistochemistry, immunofluorescence, and western blotting applications.
This antibody demonstrates minimal cross-reactivity with other related proteins, ensuring reliable and specific results. It exhibits high affinity towards DAG1, allowing for efficient and precise detection even at low expression levels. The antibody's robust performance and consistent results make it an ideal choice for both research and diagnostic purposes.
The DAG1 Polyclonal Antibody is supplied as a liquid formulation in a convenient size, ensuring ease of use and storage. It is provided in a vial with clear instructions for proper handling and usage. The antibody has a long shelf life when stored under recommended conditions, ensuring its stability and reliability over an extended period.
In summary, the DAG1 Polyclonal Antibody is a superior tool for the detection and analysis of DAG1 protein. Its exceptional sensitivity, specificity, and reliability make it an invaluable asset for researchers and clinicians working in the field of muscular dystrophies and neuromuscular disorders.
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