CYLD Polyclonal Antibody

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

The CYLD Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CYLD protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminus of human CYLD protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The CYLD Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting CYLD protein in various cell lines and tissues. It has been shown to recognize endogenous CYLD protein in human, mouse, and rat samples, and does not cross-react with other related proteins. This antibody has also been shown to detect both full-length and truncated forms of CYLD protein.

The CYLD Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles. This antibody is available in various sizes to meet the needs of different research applications.

In summary, the CYLD Polyclonal Antibody is a reliable and high-quality tool for the detection of CYLD protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of CYLD in various cellular processes.