Cyclin E1(Phospho Thr395) Polyclonal Antibody

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in

Introducing the Cyclin E1(Phospho Thr395) Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, developed with utmost precision and expertise, targets the phosphorylated threonine residue at position 395 of the Cyclin E1 protein.

The Cyclin E1(Phospho Thr395) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling accurate detection and analysis of Cyclin E1 protein phosphorylation events. Its polyclonal nature ensures a broad range of epitope recognition, enhancing the versatility and applicability of this antibody in various experimental settings.

This antibody has been rigorously validated through extensive testing, guaranteeing its reliability and reproducibility. Its exceptional performance in immunohistochemistry, immunofluorescence, and Western blotting techniques further solidifies its position as an indispensable tool for investigating the intricate mechanisms underlying cell cycle regulation and proliferation.

The Cyclin E1(Phospho Thr395) Polyclonal Antibody is manufactured using state-of-the-art techniques and adheres to the highest quality standards. It is meticulously purified to eliminate any potential cross-reactivity, ensuring unparalleled specificity and accuracy in experimental results.

With its exceptional performance, reliability, and versatility, the Cyclin E1(Phospho Thr395) Polyclonal Antibody is an invaluable asset for researchers seeking to unravel the complexities of cell cycle control and its implications in various physiological and pathological processes. Invest in this cutting-edge antibody and unlock new avenues of scientific discovery in the realm of molecular biology.