Cyclin D2(Phospho Thr280) Polyclonal Antibody

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencep

Introducing the Cyclin D2(Phospho Thr280) Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, developed with utmost precision and expertise, targets the phosphorylated threonine 280 residue of the Cyclin D2 protein, enabling accurate and reliable detection of this specific post-translational modification.

With its polyclonal nature, this antibody exhibits exceptional sensitivity and specificity, ensuring optimal results in various applications such as immunohistochemistry, western blotting, and immunofluorescence. Its ability to recognize and bind to the phosphorylated threonine 280 residue of Cyclin D2 with high affinity guarantees precise and robust detection, facilitating in-depth investigations into the intricate mechanisms underlying cell cycle regulation.

The Cyclin D2(Phospho Thr280) Polyclonal Antibody is meticulously validated through rigorous quality control measures, ensuring consistent and reproducible performance. Its exceptional specificity is further enhanced by its minimal cross-reactivity with other phosphorylated residues, ensuring accurate and reliable results without any interference from non-specific binding.

This antibody is supplied in a convenient and user-friendly format, allowing for easy integration into existing laboratory protocols. Its long shelf life and stability ensure prolonged usability, making it an ideal choice for long-term research projects.

In summary, the Cyclin D2(Phospho Thr280) Polyclonal Antibody is a highly specialized and reliable tool that empowers researchers and scientists to delve deeper into the intricate world of molecular biology. With its exceptional sensitivity, specificity, and ease of use, this antibody is poised to revolutionize the field, enabling groundbreaking discoveries and advancements in our understanding of cell cycle regulation.