Crystallin-alphaB(Phospho Ser19) Polyclonal Antibody

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

The Crystallin-alphaB(Phospho Ser19) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Crystallin-alphaB protein phosphorylated at Serine 19. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target protein.

Crystallin-alphaB is a member of the small heat shock protein family and plays a crucial role in maintaining cellular homeostasis under stress conditions. Phosphorylation of Crystallin-alphaB at Serine 19 has been implicated in various cellular processes, including cell survival, apoptosis, and cytoskeletal organization.

The Crystallin-alphaB(Phospho Ser19) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Crystallin-alphaB in various biological samples.

This antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It has been optimized for use in a wide range of species, including human, mouse, and rat, ensuring its versatility and applicability in diverse research settings.

With its exceptional performance characteristics and broad application potential, the Crystallin-alphaB(Phospho Ser19) Polyclonal Antibody is an indispensable tool for researchers studying the role of Crystallin-alphaB phosphorylation in cellular processes and disease pathogenesis.