CPI-17(Phospho Thr38) Polyclonal Antibody

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

The CPI-17(Phospho Thr38) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CPI-17 protein phosphorylated at threonine 38. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target protein.

The CPI-17 protein plays a crucial role in the regulation of smooth muscle contraction and relaxation. Phosphorylation of CPI-17 at threonine 38 has been shown to modulate its activity, leading to the regulation of smooth muscle tone. Therefore, the detection and quantification of phosphorylated CPI-17 at threonine 38 is of great importance in understanding the underlying mechanisms of smooth muscle function.

This polyclonal antibody has been extensively validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated CPI-17 and other related proteins, ensuring accurate and reliable results.

The CPI-17(Phospho Thr38) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the CPI-17(Phospho Thr38) Polyclonal Antibody is a valuable tool for researchers studying smooth muscle function and its regulation. Its high specificity, sensitivity, and versatility make it an ideal choice for the detection and quantification of phosphorylated CPI-17 at threonine 38, facilitating a deeper understanding of the molecular mechanisms underlying smooth muscle contraction and relaxation.