CP2C9 Polyclonal Antibody

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

The CP2C9 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the human CP2C9 protein. The resulting polyclonal antibody has been purified and characterized to ensure high specificity and sensitivity.

The CP2C9 Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human samples and has been shown to detect endogenous levels of CP2C9 protein in various tissues and cell lines.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications.

Overall, the CP2C9 Polyclonal Antibody is a reliable and high-quality tool for researchers studying the CP2C9 protein and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for a wide range of applications.