Cot(Phospho Ser400) Polyclonal Antibody

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.

The Cot(Phospho Ser400) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cot protein phosphorylated at serine 400. This antibody has been rigorously validated and exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its polyclonal nature, this antibody offers superior sensitivity and specificity, ensuring reliable and accurate results. It has been meticulously developed using advanced techniques and high-quality materials to guarantee consistent performance and reproducibility.

The Cot(Phospho Ser400) Polyclonal Antibody is an invaluable tool for researchers studying the role of Cot protein phosphorylation in various cellular processes and diseases. Its ability to specifically recognize and bind to the phosphorylated form of serine 400 on Cot protein enables precise investigation of signaling pathways and protein interactions.

This antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into experimental workflows. Its exceptional performance, combined with its versatility and reliability, makes it an essential component for any laboratory conducting research in the field of molecular biology and cellular signaling.

Order the Cot(Phospho Ser400) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of Cot protein phosphorylation. Experience the confidence and accuracy that this high-quality antibody brings to your research endeavors.