COPG1 Polyclonal Antibody

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.,Belongs to the COPG family.,Contains 4 HEAT repeats.,subcellular location:The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.,subunit:Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Interacts with ZNF289/ARFGAP2 through its C-terminal appendage domain.,

The COPG1 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of COPG1 protein expression. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the COPG1 protein. It has been rigorously tested and validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The COPG1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the target protein, ensuring accurate and reliable results. It recognizes endogenous levels of COPG1 protein in a wide range of species, making it suitable for use in diverse research settings. With its superior sensitivity, this antibody enables the detection of even low-abundance COPG1 protein, facilitating detailed investigations into its cellular localization and functional roles.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The COPG1 Polyclonal Antibody is manufactured under strict quality control measures to ensure consistent performance and reproducibility.

In summary, the COPG1 Polyclonal Antibody is an indispensable tool for researchers studying COPG1 protein expression and its biological significance. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, enabling comprehensive investigations into the intricate mechanisms underlying COPG1-mediated cellular processes.