Connexin 43(Phospho Ser261) Polyclonal Antibody

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

The Connexin 43(Phospho Ser261) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Connexin 43 protein phosphorylated at Serine 261. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and accuracy in various applications.

Connexin 43 is a crucial protein involved in intercellular communication through gap junction channels. Phosphorylation of Connexin 43 at Serine 261 has been shown to play a significant role in regulating its function and cellular localization. Therefore, the Connexin 43(Phospho Ser261) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms underlying cellular communication and gap junction dynamics.

This antibody exhibits exceptional specificity towards the phosphorylated form of Connexin 43 at Serine 261, enabling precise detection and quantification of this modified protein. It has been extensively validated through various experimental approaches, including Western blotting, immunofluorescence, and immunohistochemistry, ensuring reliable and reproducible results.

The Connexin 43(Phospho Ser261) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy handling and convenient use in diverse laboratory settings. It is provided in a sufficient quantity to accommodate multiple experiments, minimizing the need for frequent reordering.

With its superior performance, specificity, and versatility, the Connexin 43(Phospho Ser261) Polyclonal Antibody is an indispensable tool for researchers investigating the intricate signaling pathways and functional roles of Connexin 43 phosphorylation. Its application in various research areas, including cell biology, neuroscience, and cancer research, makes it an essential addition to any laboratory seeking to advance scientific knowledge and understanding.