Collagen IV Polyclonal Antibody

This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

Introducing the Collagen IV Polyclonal Antibody, a cutting-edge product meticulously developed by BT Lab, now available at Dana Biosciences. This highly specialized antibody is designed to target and detect Collagen IV, a crucial component of the extracellular matrix, with exceptional precision and sensitivity.

Crafted with utmost care and scientific expertise, the Collagen IV Polyclonal Antibody offers researchers an invaluable tool for various applications, including immunohistochemistry, immunofluorescence, and Western blotting. Its exceptional specificity ensures accurate identification and localization of Collagen IV in diverse biological samples, enabling researchers to gain deeper insights into cellular processes and tissue organization.

The Collagen IV Polyclonal Antibody boasts an impressive range of features that set it apart from conventional antibodies. Its high affinity and low background noise guarantee reliable and reproducible results, while its broad reactivity across multiple species, including human, mouse, and rat, enhances its versatility and applicability in various experimental settings.

Furthermore, this antibody is manufactured using state-of-the-art techniques, ensuring batch-to-batch consistency and exceptional quality control. Its long shelf life and stability make it an ideal choice for long-term storage and repeated experiments, providing researchers with a reliable and cost-effective solution.

With the Collagen IV Polyclonal Antibody from BT Lab, researchers can confidently delve into the intricate world of Collagen IV biology, unraveling its role in tissue development, disease progression, and therapeutic interventions. Elevate your research endeavors with this exceptional antibody, now available at Dana Biosciences.