Cofilin(Phospho Ser3) Polyclonal Antibody

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

The Cofilin(Phospho Ser3) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cofilin protein phosphorylated at Serine 3. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Cofilin is a key regulator of actin dynamics, playing a crucial role in various cellular processes such as cell migration, cytoskeletal organization, and cell division. Phosphorylation of Cofilin at Serine 3 is known to modulate its activity, leading to alterations in actin filament turnover and cellular morphology.

The Cofilin(Phospho Ser3) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Cofilin in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for compatibility with a wide range of experimental conditions, ensuring consistent and reproducible results. The Cofilin(Phospho Ser3) Polyclonal Antibody is suitable for use in both research and clinical settings, facilitating investigations into the role of Cofilin phosphorylation in various physiological and pathological processes.

With its exceptional performance and versatility, the Cofilin(Phospho Ser3) Polyclonal Antibody is an indispensable tool for researchers and scientists studying actin dynamics, cellular processes, and signaling pathways. Its high specificity and sensitivity make it an ideal choice for accurate and reliable detection of phosphorylated Cofilin, enabling deeper insights into the intricate mechanisms governing cellular functions.