CO3 Polyclonal Antibody

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

The CO3 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CO3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CO3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CO3 protein, making it an ideal tool for various research applications.

The CO3 Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, and has been shown to detect CO3 protein in a variety of tissues and cell types.

This antibody is supplied as a purified IgG fraction, and has been extensively characterized for its specificity and sensitivity. It is provided in a convenient format, with a concentration of 1 mg/mL, and can be used at a recommended dilution of 1:1000 for most applications.

Overall, the CO3 Polyclonal Antibody is a reliable and high-quality reagent that can be used for the detection and quantification of CO3 protein in a variety of biological samples. Its high specificity and sensitivity make it an ideal tool for researchers studying the role of CO3 protein in various physiological and pathological processes.