BT Lab
SKU:BT-AP14954
Chk1(Phospho Ser317) Polyclonal Antibody
Chk1(Phospho Ser317) Polyclonal Antibody
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The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Introducing the Chk1(Phospho Ser317) Polyclonal Antibody, a highly specialized and meticulously developed product designed to facilitate advanced research in the field of cellular biology. This antibody, derived from a polyclonal source, has been specifically engineered to target and detect the phosphorylated form of Chk1 at Serine 317.
With its exceptional specificity and sensitivity, the Chk1(Phospho Ser317) Polyclonal Antibody offers researchers an invaluable tool for investigating the intricate mechanisms underlying cellular processes such as DNA damage response, cell cycle regulation, and checkpoint control. By selectively binding to the phosphorylated Chk1 at Serine 317, this antibody enables precise visualization and quantification of this critical protein modification.
Crafted with utmost precision and rigorously validated, this antibody guarantees reliable and reproducible results, ensuring the utmost confidence in experimental outcomes. Its exceptional affinity for the phosphorylated Chk1 at Serine 317 ensures minimal cross-reactivity, thereby minimizing any potential interference from non-specific binding events.
The Chk1(Phospho Ser317) Polyclonal Antibody is compatible with a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into various experimental protocols, facilitating comprehensive investigations into the role of Chk1 phosphorylation in diverse biological contexts.
Furthermore, this antibody has been meticulously formulated to exhibit exceptional stability and longevity, ensuring consistent performance over extended periods of storage. Its robust design and stringent quality control measures guarantee optimal functionality, making it an indispensable asset for any laboratory engaged in cutting-edge research.
In summary, the Chk1(Phospho Ser317) Polyclonal Antibody represents a pinnacle of scientific innovation, offering researchers an unparalleled tool to unravel the complexities of cellular biology. With its exceptional specificity, sensitivity, and compatibility with various applications, this antibody is poised to revolutionize the field, enabling groundbreaking discoveries and advancing our understanding of fundamental biological processes.
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