CENPP Polyclonal Antibody

CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006

The CENPP Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CENPP protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CENPP protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The CENPP protein is a key component of the kinetochore, a protein complex that plays a critical role in chromosome segregation during cell division. Dysregulation of CENPP expression has been implicated in various human diseases, including cancer. Therefore, the CENPP Polyclonal Antibody is an essential tool for researchers studying the role of CENPP in normal and pathological cellular processes.

This antibody exhibits high specificity and sensitivity, enabling the detection of even low levels of CENPP protein in complex biological samples. It has been extensively validated for use in various applications, ensuring reliable and reproducible results. The CENPP Polyclonal Antibody is supplied in a convenient format, making it easy to use in a wide range of experimental settings.

In summary, the CENPP Polyclonal Antibody is a highly specific and sensitive tool for the detection of CENPP protein in various biological samples. Its high quality and reliability make it an essential reagent for researchers studying the role of CENPP in cellular processes and disease.