CENP-A(Phospho Ser7) Polyclonal Antibody

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

The CENP-A(Phospho Ser7) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CENP-A protein phosphorylated at Ser7 residue. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The CENP-A(Phospho Ser7) Polyclonal Antibody is ideal for use in a wide range of applications, including western blotting, immunoprecipitation, and immunofluorescence. This antibody is suitable for use in both research and diagnostic applications, and it is available in a variety of sizes to meet the needs of different users. The CENP-A(Phospho Ser7) Polyclonal Antibody is a reliable and effective tool for the detection of CENP-A protein phosphorylated at Ser7 residue, making it an essential component of any laboratory's research toolkit.

The CENP-A(PHOSPHO SER7) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CENP-A protein phosphorylated at serine 7. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

CENP-A is a centromere-specific histone H3 variant that plays a crucial role in the assembly and maintenance of centromeric chromatin. Phosphorylation of CENP-A at serine 7 has been implicated in various cellular processes, including mitotic progression and chromosome segregation. Therefore, the ability to accurately detect and quantify this phosphorylation event is of utmost importance in understanding the underlying mechanisms of cell division and genome stability.

The CENP-A(PHOSPHO SER7) Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its high sensitivity allows for the detection of low-abundance phosphorylated CENP-A species, enabling researchers to obtain reliable and reproducible results.

This antibody has been extensively validated using various cell lines and tissues, ensuring its reliability and consistency across different experimental conditions. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation steps.

In summary, the CENP-A(PHOSPHO SER7) Polyclonal Antibody is an indispensable tool for researchers studying centromere biology and its implications in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, providing valuable insights into the intricate mechanisms governing genome stability and cell division.