CD42c Polyclonal Antibody

Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, t

The CD42c Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CD42c protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The CD42c Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry.

This antibody is designed to recognize the CD42c protein, which is a platelet-specific glycoprotein that plays a crucial role in platelet aggregation and thrombus formation. The CD42c Polyclonal Antibody is highly specific for CD42c and does not cross-react with other platelet glycoproteins or non-platelet proteins.

The CD42c Polyclonal Antibody is supplied in a convenient format that is easy to use and store. It is available in various sizes to suit different experimental needs. This antibody is manufactured to the highest standards of quality and purity, ensuring consistent and reliable results.

In summary, the CD42c Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of CD42c protein in various biological samples. It is a valuable tool for researchers studying platelet function and thrombosis, and it is manufactured to the highest standards of quality and purity.