CD2AP Polyclonal Antibody

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

The CD2AP Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD2AP protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.

CD2AP, also known as CD2-associated protein, plays a crucial role in the regulation of cell adhesion and migration. It is involved in the formation and maintenance of the podocyte slit diaphragm, a specialized structure in the kidney essential for proper filtration. CD2AP is also implicated in the organization of the immune synapse, a critical step in T cell activation.

The CD2AP Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of CD2AP protein, enabling accurate quantification and localization studies.

With its high specificity and sensitivity, this antibody is an invaluable tool for researchers studying the role of CD2AP in various physiological and pathological processes. It provides reliable and reproducible results, facilitating a deeper understanding of CD2AP function and its potential implications in disease mechanisms.

The CD2AP Polyclonal Antibody is supplied in a convenient format, ensuring ease of use and storage. It is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and optimal performance.

In summary, the CD2AP Polyclonal Antibody is a superior reagent for the detection and analysis of CD2AP protein expression. Its exceptional specificity, sensitivity, and reliability make it an essential tool for researchers in the fields of cell biology, immunology, and kidney research.