CD275 Polyclonal Antibody

alternative products:Additional isoforms seem to exist,Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.,induction:Constitutive expression is further enhanced by treatment with TNF-alpha in peripheral blood B-cells and monocytes, while it is decreased in dendritic cells.,sequence The sequence differs from that shown in position 300 onward for unknown reason.,sequence Translation N-terminally shortened.,Belongs to the immunoglobulin superfamily. BTN/MOG family.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.,

The CD275 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CD275 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for their specificity and sensitivity. The CD275 Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry.

This antibody is designed to recognize the CD275 protein, which is a member of the B7 family of co-stimulatory molecules. CD275 is expressed on the surface of activated T cells and plays a critical role in regulating T cell activation and proliferation. The CD275 Polyclonal Antibody is an essential tool for researchers studying the immune system and its role in various diseases.

The CD275 Polyclonal Antibody is supplied in a convenient format, making it easy to use in a variety of applications. It is available in different sizes to suit the needs of different experiments. This antibody has been extensively tested and validated to ensure its high specificity and sensitivity, making it a reliable tool for researchers.

In summary, the CD275 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for researchers studying the immune system and its role in various diseases. Its high-quality production and validation make it a reliable tool for a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry.