CD1B Polyclonal Antibody

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

The CD1B Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CD1B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CD1B protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CD1B protein, making it an ideal tool for various research applications.

The CD1B Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other CD1 family members. This antibody is supplied as a purified IgG fraction, and has been tested for its ability to detect endogenous CD1B protein in various cell lines and tissues.

In summary, the CD1B Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of CD1B protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of CD1B in various physiological and pathological processes.