CD130/gp130(Phospho-Ser782) Polyclonal Antibody

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

The CD130/gp130(Phospho-Ser782) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CD130/gp130 protein phosphorylated at Ser782. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

CD130/gp130 is a transmembrane protein that belongs to the cytokine receptor family. It plays a crucial role in the signal transduction of various cytokines, including interleukin-6 (IL-6) and IL-11. Phosphorylation of CD130/gp130 at Ser782 has been implicated in the regulation of downstream signaling pathways, leading to diverse cellular responses.

This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of CD130/gp130 phosphorylated at Ser782 in complex biological samples.

The CD130/gp130(Phospho-Ser782) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is optimized for use in diverse research areas, including cell signaling, immunology, and cancer biology.

With its exceptional performance and reliability, the CD130/gp130(Phospho-Ser782) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the role of CD130/gp130 phosphorylation in various biological processes.