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SKU:BT-AP14603

CAD12 Polyclonal Antibody

CAD12 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.

The CAD12 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CAD12 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional specificity, the CAD12 Polyclonal Antibody enables accurate identification and quantification of CAD12 protein levels in a wide range of research applications.

The CAD12 Polyclonal Antibody exhibits excellent performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) assays. It recognizes the CAD12 protein with utmost precision, allowing for precise localization and visualization of CAD12 expression in tissues and cells. Moreover, this antibody demonstrates minimal cross-reactivity with other proteins, ensuring reliable and reproducible results.

This CAD12 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The antibody is rigorously tested for its performance and quality control to ensure consistent and reliable results.

In summary, the CAD12 Polyclonal Antibody is an indispensable tool for researchers studying CAD12 protein expression. Its exceptional specificity, high affinity, and reliable performance make it an ideal choice for various applications, including IHC, IF, and WB. With this antibody, researchers can confidently investigate the role of CAD12 in biological processes and gain valuable insights into its function.

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