CAC1E Polyclonal Antibody

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

The CAC1E Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region of the CAC1E protein. The resulting polyclonal antibody exhibits high affinity and specificity for the CAC1E protein, making it an ideal tool for detecting and quantifying CAC1E expression in various biological samples.

The CAC1E Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to detect endogenous levels of CAC1E protein in various tissues and cell lines, and can be used to study the role of CAC1E in various cellular processes.

This antibody is supplied as a purified IgG fraction, and has been tested for its ability to recognize the CAC1E protein in various species, including human, mouse, and rat. It is recommended for use at a dilution of 1:1000 for Western blotting, and 1:200 for immunohistochemistry and immunofluorescence assays.

Overall, the CAC1E Polyclonal Antibody is a reliable and effective tool for studying the expression and function of the CAC1E protein in various biological systems. Its high specificity and sensitivity make it an ideal choice for researchers looking to investigate the role of CAC1E in various cellular processes.